KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFF1
All Species:
5.45
Human Site:
S212
Identified Species:
17.14
UniProt:
P51825
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51825
NP_005926.1
1210
131422
S212
P
S
P
V
P
P
L
S
P
I
H
S
N
Q
Q
Chimpanzee
Pan troglodytes
Q7YQM2
1272
140491
G203
P
A
E
Q
P
Q
I
G
E
A
E
E
S
N
P
Rhesus Macaque
Macaca mulatta
XP_001095677
1221
132380
S220
P
S
P
V
P
P
L
S
P
I
H
S
N
Q
Q
Dog
Lupus familis
XP_850309
1163
127349
S192
Q
A
V
S
S
L
S
S
S
H
S
R
S
H
G
Cat
Felis silvestris
Mouse
Mus musculus
O88573
1217
131756
P198
S
P
V
P
P
L
S
P
V
H
S
R
L
Q
G
Rat
Rattus norvegicus
NP_001100676
1170
127233
L207
L
P
S
P
V
P
P
L
S
P
A
H
S
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515909
1378
146836
G360
S
T
L
S
S
P
V
G
P
L
S
P
L
H
S
Chicken
Gallus gallus
XP_420549
1247
137025
V256
L
P
S
L
S
S
P
V
A
P
L
S
P
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
95.5
39.1
N.A.
69.7
65.6
N.A.
51
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
46.6
96.5
56.4
N.A.
78.8
74.7
N.A.
63.5
64.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
6.6
N.A.
13.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
20
N.A.
13.3
20
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
0
0
13
13
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
0
0
0
0
0
13
0
13
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
25
25
13
0
25
13
% H
% Ile:
0
0
0
0
0
0
13
0
0
25
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
13
13
0
25
25
13
0
13
13
0
25
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
25
13
0
% N
% Pro:
38
38
25
25
50
50
25
13
38
25
0
13
13
0
25
% P
% Gln:
13
0
0
13
0
13
0
0
0
0
0
0
0
38
25
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
25
0
13
0
% R
% Ser:
25
25
25
25
38
13
25
38
25
0
38
38
38
0
13
% S
% Thr:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
25
25
13
0
13
13
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _